Open AccessFollicular graft-versus-host disease: A rare manifestation in a patient with the overlap subtype of chronic graft-versus-host disease
Author(s) -
YiHsin Ho,
YunWen Chiu,
HanNan Liu
Publication year - 2019
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/ijd.ijd_412_18
Subject(s) - medicine , graft versus host disease , disease , hematopoietic stem cell transplantation , complication , follicular phase , erythema , dermatology , rare disease , pathology
Graft-versus-host disease (GVHD) is a frequent and potentially life-threatening complication of hematopoietic stem cell transplantation (HSCT). Although skin involvement is common, generalized follicular eruption as the major clinical manifestation is rare. However, it is important for clinicians to recognize it at the earliest to initiate an appropriate therapy. We report a case of a patient with multiple myeloma who developed extensive hyperkeratotic, lichenoid folliculocentric papules with perifollicular erythema on day 53 following an allogeneic HSCT. The overall clinical and histological findings were consistent with the overlap subtype of chronic follicular GVHD.