Open AccessComparison of efficacy of doxycycline and isotretinoin on cutaneous human beta-defensin-1 and -2 levels in acne vulgaris
Author(s) -
Gülhan Aksoy,
Esra Adışen,
Özlem Erdem,
A. Burhan Aksakal
Publication year - 2018
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/ijd.ijd_402_16
Subject(s) - doxycycline , medicine , isotretinoin , acne , pathogenesis , beta defensin , dermatology , antimicrobial , minocycline , gastroenterology , immunology , immune system , antibiotics , innate immune system , microbiology and biotechnology , biology
Recent studies have shown that human beta-defensin-1 (hBD-1) and (human beta-defensin-2 hBD-2), which are antimicrobial peptides produced by the skin, play a role in the pathogenesis of acne vulgaris (AV).