Open AccessA randomized, double-blind study of amorolfine 5% nail lacquer with oral fluconazole compared with oral fluconazole alone in the treatment of fingernail onychomycosis
Author(s) -
Somodyuti Chandra,
Karan Sancheti,
Indrashis Podder,
Anupam Das,
Tushar Kanti Sarkar,
Moitreyee Chowdhury,
Abheek Sil,
Susmita Bhattacharya,
Nilay Kanti Das
Publication year - 2019
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/ijd.ijd_385_17
Subject(s) - fluconazole , medicine , nail (fastener) , itraconazole , dermatology , lacquer , randomized controlled trial , minimum inhibitory concentration , antifungal , pharmacology , surgery , microbiology and biotechnology , antibiotics , biology , chemistry , materials science , organic chemistry , metallurgy , coating
It is a challenge to treat onychomycosis due to frequent treatment failures and relapses. Systemic and topical therapies need to be combined to improve cure rates. Antifungal susceptibility might play a role in the treatment resistance of onychomycosis.