Hydroa vacciniforme-like lymphoma with systemic symptoms: Two case reports | Zendy

Guiying Zhang | Zendy; Litao Wang | Zendy; Yuwen Su | Zendy; Jianzhong Zhang | Zendy; Wen Hai-quan | Zendy

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Hydroa vacciniforme-like lymphoma with systemic symptoms: Two case reports

Author(s) -

Guiying Zhang,

Litao Wang,

Yuwen Su,

Jianzhong Zhang,

Wen Hai-quan

Publication year - 2019

Publication title -

indian journal of dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.395

H-Index - 36

eISSN - 1998-3611

pISSN - 0019-5154

DOI - 10.4103/ijd.ijd_178_18

Subject(s) - medicine , dermatology , lymphoma , pathology

Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER. Taken together, both the patients were diagnosed with hydroa vacciniforme-like lymphoma. Two patients showed significant improvement in clinical symptoms after being treated with acyclovir, low dose predisone and IFN-α.

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