Open AccessHydroa vacciniforme-like lymphoma with systemic symptoms: Two case reports
Author(s) -
Litao Wang,
Su Y,
Jianzhong Zhang,
Hao Wen,
Guiying Zhang
Publication year - 2019
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/ijd.ijd_178_18
Subject(s) - medicine , dermis , lymphoma , skin biopsy , dermatology , biopsy , immunohistochemistry , lesion , pathology , atypical lymphocyte
Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER. Taken together, both the patients were diagnosed with hydroa vacciniforme-like lymphoma. Two patients showed significant improvement in clinical symptoms after being treated with acyclovir, low dose predisone and IFN-α.