
Cefazolin and an aminoglycoside compared with cefazolin alone for the antimicrobial prophylaxis of type iii open orthopedic fractures
Author(s) -
Shawn Depcinski,
Katherine Nguyen,
Peter T. Ender
Publication year - 2019
Publication title -
international journal of critical illness and injury science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.274
H-Index - 12
eISSN - 2231-5004
pISSN - 2229-5151
DOI - 10.4103/ijciis.ijciis_7_19
Subject(s) - cefazolin , medicine , odds ratio , aminoglycoside , confidence interval , orthopedic surgery , context (archaeology) , surgery , retrospective cohort study , antibiotics , microbiology and biotechnology , biology , paleontology
Uncertainty of antibiotic prophylaxis of type III open orthopedic fractures still exists. Controversy remains as using cefazolin as a single agent or the addition of an aminoglycoside for broader coverage to prevent infection.