Open AccessRole of central venous oxygen saturation in prognostication of patients with severe sepsis and septic shock in emergency medical services
Author(s) -
Susheel Kumar,
Gauri Jangpangi,
Ashish Bhalla,
Navneet Sharma
Publication year - 2019
Publication title -
international journal of critical illness and injury science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.274
H-Index - 12
eISSN - 2231-5004
pISSN - 2229-5151
DOI - 10.4103/ijciis.ijciis_19_19
Subject(s) - medicine , septic shock , resuscitation , sepsis , central venous catheter , early goal directed therapy , shock (circulatory) , pulmonary artery catheter , cohort , randomized controlled trial , emergency medicine , intensive care medicine , surgery , catheter , severe sepsis , hemodynamics , cardiac output
All the components of early goal-directed therapy, especially central venous oxygen saturation (ScvO 2 ) as one of the endpoints of resuscitation, may not have mortality benefit, more so after results of the Australasian Resuscitation of Sepsis Evaluation, A Randomized Trial of Protocol-Based Care for Early Septic Shock, and The Protocolised Management in Sepsis trials. However, extrapolating results from trials undertaken in the developed world may not be entirely appropriate.