Open AccessComparision of analgesic efficacy of tramadol infusion versus tramadol plus ondansetron infusion in medical intensive care unit
Author(s) -
Surya Prakash Yarramalle,
Kartik Munta,
S Manimala Rao,
Pradeep M Venkategowda,
Sagar Sunka,
Sai Kiran Dudam
Publication year - 2018
Publication title -
indian journal of critical care medicine/indian journal of critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 30
eISSN - 1998-359X
pISSN - 0972-5229
DOI - 10.4103/ijccm.ijccm_5_17
Subject(s) - tramadol , medicine , anesthesia , ondansetron , analgesic , tramadol hydrochloride , antiemetic , intensive care unit , nausea , intensive care medicine
Tramadol, a preferred analgesic due to its less respiratory depression. It also has a central action that blocks the reuptake and enhances the release of serotonin at spinal antinociceptive pathways. Ondansetron, an antiemetic is a serotonin receptor antagonist. Due to the contradictory actions of the two drugs, co-administration of these drugs resulted in higher usage of tramadol. All these studies were done in the postoperative period.