Open AccessConcurrent coronary, left ventricle, and cerebral thrombosis – A trilogy
Author(s) -
Monika Bhandari,
Akshyaya Pradhan,
Pravesh Vishwakarma,
Rishi Sethi
Publication year - 2022
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/ijabmr.ijabmr_95_21
Subject(s) - medicine , cardiology , thrombolysis , thrombus , myocardial infarction , ventricle , left ventricular thrombus , antithrombotic , stroke (engine) , coronary thrombosis , thrombosis , percutaneous coronary intervention , mechanical engineering , engineering
Left ventricular (LV) thrombus is a known complication of acute myocardial infarction (AMI), especially anterior wall MI and leads to systemic thromboembolism. However, increase in the rates of coronary perfusion either by thrombolysis or percutaneous interventions have reduced its incidence. Concurrent stroke and MI are seen in 0.009% of cases. The occurrence of AMI with LV thrombus with or without stroke mandates the combination of antiplatelet and antithrombotic therapy. Hitherto, there are no randomized studies in the setting of AMI with LV thrombus comparing dual (single antiplatelet plus oral anticoagulant [OAC]) and triple therapy (dual antiplatelet therapy with OAC). There are no large randomized trials as well to delineate the optimal therapy for simultaneous cardiac and cerebral infarction. We hereby, report an unusual case of a young patient who presented with triple combo of acute anterior wall MI, LV thrombus, and ischemic stroke and discuss the challenges in management in this scenario.