Open AccessSertoli-leydig cell tumor of ovary: A rare case report with heterologous elements and focal marked anaplasia
Author(s) -
Parul Gautam,
Meenakshi Rao,
Meenakshi Gothwal,
Pawan Kumar Garg,
Susmita Bhattacharya
Publication year - 2019
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/ijabmr.ijabmr_84_18
Subject(s) - anaplasia , heterologous , ovary , virilization , pathology , neoplasm , stromal cell , biology , medicine , hormone , androgen , biochemistry , gene
Sertoli-Leydig cell tumor (SLCT) of the ovary is an extremely uncommon neoplasm accounting for <0.5% of all primary ovarian neoplasms. These tumors belong to the category of sex cord-stromal tumors. The tumor has variable clinical and histopathological presentations complicating the diagnosis and therefore the treatment. The presence of heterologous elements is seen in one-fifth of these already rare neoplasms. Herein, we report a case of a 28-year-old female presenting with irregular menses, features of virilization, and abdominal pain. Histopathological examination revealed marked focal anaplasia in this tumor of, otherwise, intermediate differentiation along with the presence of heterologous elements. Reporting of such elements is imperative for adequate treatment and deciding follow-up.