Open AccessIncreasing prevalence of Escherichia coli and Klebsiella pneumoniae producing CTX-M-type extended-spectrum beta-lactamase, carbapenemase, and NDM-1 in patients from a rural community with community acquired infections: A 3-year study
Author(s) -
Leimapokpam Sumitra Devi,
Shobha Broor,
Rajendra Singh Rautela,
Shyam Sunder Grover,
Anita Chakravarti,
Debasish Chattopadhya
Publication year - 2020
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/ijabmr.ijabmr_360_19
Subject(s) - klebsiella pneumoniae , cefotaxime , beta lactamase , microbiology and biotechnology , biology , antibiotics , escherichia coli , antibiotic resistance , gene , genetics
Increasing prevalence of community-acquired infections (CAIs) due to Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamase (ESBL), especially the Cefotaxime-Munich (CTX-M) type, carbapenemase, and New Delhi metallo-β-lactamase (NDM), has been reported globally posing a serious public health threat that has complicated treatment strategies for Gram-negative bacterial infections. While most of the reports in this regard are based on hospitalized patients from the urban community, there is a paucity of data in a rural community presenting with CAIs.