Open AccessImmunoglobulin a myeloma in a newly diagnosed sickle cell disease patient
Author(s) -
John Ayodele Olaniyi,
Khadijah Bolanle Shonde-Adebola
Publication year - 2018
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/ijabmr.ijabmr_107_17
Subject(s) - medicine , multiple myeloma , plasmacytosis , anemia , bone marrow , antibody , gastroenterology , pediatrics , pathology , immunology
Several neoplasms including hematological malignancies occurring in very few patients with sickle cell syndromes have been reported in literature, particularly as survival among these patients and diagnostic accuracy have continued to improve. Multiple myeloma (MM) has rarely been reported in patients with hemoglobin (Hb) S + C. We report a 65-year-old retired banker who was recently diagnosed with HbS + C. This patient developed MM with markedly elevated erythrocyte sedimentation rate, mild anemia, 80% bone marrow plasmacytosis, and elevated serum immunoglobulin A level, while plain X-ray of the lumbosacral spine showed multilevel vertebral collapse.