Open AccessPerioperative management of patients with severe hypophosphataemia secondary to oncogenic osteomalacia: Our experience and review of literature
Author(s) -
Alka Verma,
Saipriya Tewari,
Ashish Kannaujia
Publication year - 2017
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/ija.ija_57_17
Subject(s) - medicine , osteomalacia , perioperative , craniofacial , vitamin d and neurology , soft tissue , resection , surgery , psychiatry
Oncogenic osteomalacia (OOM) is a rare paraneoplastic syndrome associated with mesenchymal tumours. It is characterised by phosphaturia, hypophosphataemia, decreased serum Vitamin D3 levels and severe osteomalacia. OOM-inducing tumours are usually benign, arising either from bone or soft tissue, with extremities and craniofacial region being the most common sites. Surgical resection of the tumour remains the mainstay of treatment. Challenges to an anaesthesiologist arise when such patients are planned for surgical resection of the underlying tumour. All the perioperative dilemmas are directly related to the severe hypophosphataemia. We describe three such cases of OOM and their perioperative management.