Open AccessCurrent use of ivermectin in dermatology, tropical medicine, and COVID-19: An update on pharmacology, uses, proven and varied proposed mechanistic action
Author(s) -
Sinu Rose Mathachan,
Kabir Sardana,
Ananta Khurana
Publication year - 2021
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/idoj.idoj_298_21
Subject(s) - ivermectin , medicine , covid-19 , hydroxychloroquine , drug , clinical pharmacology , antiparasitic agent , antiparasitic , broad spectrum , pharmacology , drug reaction , drug repositioning , dermatology , intensive care medicine , veterinary medicine , pathology , chemistry , combinatorial chemistry , disease , infectious disease (medical specialty)
Ivermectin is a broad-spectrum antiparasitic drug with anti-inflammatory, anti-viral, anti-bacterial, and anti-tumor effects. In this review, we discuss the history, pharmacology, multimodal actions, indications in dermatology and tropical medicine, therapeutic and prophylactic use of ivermectin in COVID-19, safety, adverse effects, special considerations, and drug interactions of ivermectin.