Open AccessPapillary fibroelastoma of the left ventricle in a radiation-treated cancer patient
Author(s) -
Tomás Francisco Cianciulli,
María Cristina Saccheri,
Alberto Cozzarín,
Jorge A. Lax,
Mario Enrique Simonetti
Publication year - 2018
Publication title -
heart views
Language(s) - English
Resource type - Journals
eISSN - 0976-5123
pISSN - 1995-705X
DOI - 10.4103/heartviews.heartviews_21_18
Subject(s) - papillary fibroelastoma , medicine , radiation therapy , ventricle , mitral regurgitation , cardiology , radiology , heart failure , mitral valve , surgery , aortic valve
We present the case of a 69-year-old female patient with a history of endometrial carcinoma in 1996, who underwent a total hysterectomy and bilateral adnexectomy. The patient also received chemotherapy and mediastinal radiotherapy followed by cancer remission. Ten years later she presented with heart failure and her Doppler-echocardiogram showed severe mitral regurgitation with pulmonary hypertension and a papillary fibroelastoma in the left ventricle. In 2011, she underwent a mitral valve replacement with a biological prosthesis and the pathology exam revealed valve damage consistent with radiotherapy- induced changes and confirmed the presence of a papillary fibroelastoma. This unusual mechanism of papillary fibroelastoma should be disseminated among cardiology physicians and in patients who have survived for long periods after radiotherapy. It is important to remember that cardiac complications may indeed occur, and the treating physician is responsible for detecting them.