Open AccessA comparative evaluation of interleukin 1 beta and prostaglandin E2 with and without low-level laser therapy during En masse retraction
Author(s) -
Jeffy Ann Jose,
Sanju Somaiah,
Sunil Muddaiah,
Balakrishna Shetty,
Goutham Reddy,
S Roopa
Publication year - 2018
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/ccd.ccd_859_17
Subject(s) - low level laser therapy , periodontium , medicine , prostaglandin e2 , dentistry , pulp (tooth) , interleukin , laser therapy , orthodontics , cytokine , laser , physics , optics
Orthodontic forces are known to produce mechanical damage and inflammatory mediators such as prostaglandins (PGs) and interleukin (IL)-1, in the periodontium and dental pulp. Low-level laser therapy (LLLT) is a stimulator of the on-going biological process in tissue and found to be effective in modulating cell activity, which is involved in orthodontic tooth movement. Here, a humble effort has been made to study two such cytokines, namely IL-1 β and PG E2 (PGE2) which are partially responsible for bone turnover. The purpose of this study was to compare the changes occurring in the values of IL-1 β and PGE2 in the gingival crevicular fluid (GCF) during en masse retraction with and without LLLT.