Open AccessExtracorporeal photopheresis: Review of technical aspects
Author(s) -
Satyam Arora,
Rasika Setia
Publication year - 2017
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_87_16
Subject(s) - medicine , photopheresis , extracorporeal photopheresis , immunosuppression , immune system , intensive care medicine , extracorporeal , immunology , surgery , transplantation , graft versus host disease , lymphoma
Extracorporeal photochemotherapy (ECP) is considered as an immune modulating therapy majorly targeting the T cells of the Immune system. ECP induces an anti-inflammatory condition with tolerogenic responses without inducing a global immunosuppression state which is a typical feature of other therapeutic options such as steroids. Clinical indication of ECP has grown over time since its initial applications. Our review discusses the technical aspects of the concept of photopheresis with the available methods for its clinical applications.