Open AccessSevere hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from India
Author(s) -
Sharad Mehta,
Aseem Kumar Tiwari,
Rajesh Puri,
Dinesh Arora,
Geet Aggarwal,
Ankita Ratan
Publication year - 2018
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_86_17
Subject(s) - medicine , hypertriglyceridemia , pancreatitis , acute pancreatitis , gallstones , refractory (planetary science) , gastroenterology , therapeutic plasma exchange , surgery , intensive care medicine , triglyceride , cholesterol , physics , astrobiology
Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. He was treated with TPE along with intravenous insulin, statins, and fibrates. TPE resulted in immediate relief of symptoms as well as a marked improvement in laboratory values, with 74.5% reduction in triglycerides after a single session. TPE can be successfully utilized as an adjunct in HTG-induced pancreatitis.