Open AccessMean corpuscular volume/mean corpuscular hemoglobin values are not reliable predictors of the β-thalassemia carrier status among healthy diverse populations of Himachal Pradesh, India
Author(s) -
Omesh Kumar Bharti,
Ridhi Sood,
Hans Raj Sharma,
Harsharan Kaur,
Varinder Minhas,
Rajinder Singh Chauhan,
Nitu Nigam,
Archana Phull
Publication year - 2020
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_109_18
Subject(s) - mean corpuscular volume , thalassemia , medicine , mean corpuscular hemoglobin , mean corpuscular hemoglobin concentration , hemoglobin , red blood cell distribution width , gastroenterology , pediatrics , immunology , veterinary medicine
Himachal Pradesh is a hill state in North India in the Western Himalayas. β-thalassemia is a genetic disorder of hemoglobin inherited in an autosomal recessive manner that results in defective globin production leading to the early destruction of red blood cells. β-thalassemia has long been neglected in Himachal Pradesh due to popular belief that it runs along "Lahore-Gujarat-Punjab" belt in India. Therefore, there is no β-thalassemia testing facility currently in the state.