Open AccessPhosphaturic mesenchymal tumors involving skull bones: Report of two rare cases
Author(s) -
Toshi Mishra,
Maria Alina Desouza,
Keyuri Patel,
Girish A Mazumdar
Publication year - 2019
Publication title -
asian journal of neurosurgery
Language(s) - English
Resource type - Journals
ISSN - 1793-5482
DOI - 10.4103/ajns.ajns_176_17
Subject(s) - skull , medicine , appendicular skeleton , meningioma , soft tissue , osteomalacia , connective tissue , skeleton (computer programming) , hemangiopericytoma , pathology , occipital bone , mesenchymal stem cell , anatomy , osteoporosis
Phosphaturic mesenchymal tumor (PMT) is a rare tumor causing oncogenic osteomalacia (OO). Most such tumors occur in soft tissue and bones of extremities and appendicular skeleton. Intracranial location and involvement of temporal-occipital bone is extremely rare. We report two unusual cases: The first was intracranial, involving the temporal bone, while the other was a skull base tumor arising from the occipital-temporal bone. Both of them presented with paraneoplastic syndrome of OO, resembled a meningioma radiologically, and underwent gross total resection of tumor. Histologically, both of them were diagnosed as PMT, mixed connective tissue variant.