Open AccessEndoscopic transsphenoidal approach in treatment of germinomas of the chiasmosellar region
Author(s) -
М. А. Кутин,
Dmitry Fomichev,
A N Shkarubo,
I V Chernov,
Oleg Sharipov,
Dmitriy Andreev,
D B Ismailov,
Н. И. Михайлов,
G L Kobyakov,
Yuriy Yurievich Trunin,
Gennady Chmutin,
А. А. Абдилатипов,
Artem Andreevich Poddubsky,
Pavel Kalinin
Publication year - 2019
Publication title -
asian journal of neurosurgery
Language(s) - English
Resource type - Journals
ISSN - 2248-9614
DOI - 10.4103/ajns.ajns_156_19
Subject(s) - medicine , germinoma , biopsy , surgery , cerebrospinal fluid , radiology , chemotherapy , pathology
Germinogenic central nervous system (CNS) tumors represent a heterogeneous group of tumors, constituting approximately 0.4% of all primary brain tumors. Removal of the tumor has no prognostic value. In "pure" primary germinomas of the CNS, the alpha-fetoprotein and human chorionic gonadotropin levels are within normal limits, and no specific biochemical tumor markers currently exist for this tumor type, making histological verification crucial for the choice of treatment tactics. When the tumor is located in the chiasmosellar region, one of the possible verification methods is endoscopic endonasal transsphenoidal biopsy.