Open AccessGut microbiota and stroke
Author(s) -
Benjamin Yong-Qiang Tan,
Prakash Paliwal,
Vijay K. Sharma
Publication year - 2020
Publication title -
annals of indian academy of neurology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/aian.aian_483_19
Subject(s) - medicine , stroke (engine) , dysphagia , dysbiosis , constipation , gut flora , gut–brain axis , gut microbiome , microbiome , population , intensive care medicine , ischemic stroke , bioinformatics , immunology , surgery , ischemia , environmental health , mechanical engineering , engineering , biology
Ischemic stroke remains a significant health problem, which is expected to increase owing to an aging population. A considerable proportion of stroke patients suffer from gastrointestinal complications, including dysphagia, gastrointestinal hemorrhage, and constipation. Often, these complications adversely affect stroke outcomes. Recent research postulates the role of "brain-gut axis" in causing gut microbiota dysbiosis and various complications and outcomes. In this review, we present our current understanding about the interaction between commensal gut microbiome and brain in determining the course of stroke.