Comparative evaluation of the effects of pregabalin, dexmedetomidine, and their combination on the hemodynamic response and anesthetic requirements in patients undergoing laparoscopic cholecystectomy: A randomized double-blind prospective study | Zendy

Vandana Talwar | Zendy; N Vijayan | Zendy; Madhu Dayal | Zendy

Open Access

Comparative evaluation of the effects of pregabalin, dexmedetomidine, and their combination on the hemodynamic response and anesthetic requirements in patients undergoing laparoscopic cholecystectomy: A randomized double-blind prospective study

Author(s) -

Vandana Talwar,

N Vijayan,

Madhu Dayal

Publication year - 2019

Publication title -

anesthesia essays and researches

Language(s) - English

Resource type - Journals

ISSN - 0259-1162

DOI - 10.4103/aer.aer_86_19

Subject(s) - medicine , dexmedetomidine , anesthesia , pneumoperitoneum , premedication , pregabalin , propofol , sedation , surgery , laparoscopy

In this study, we evaluated the efficacy of premedication with dexmedetomidine, pregabalin, and dexmedetomidine-pregabalin combination for attenuating the haemodynamic stress response to laryngoscopy and intubation and pneumoperitoneum (primary outcome), and for reducing anaesthetic requirement (secondary outcome) in patients undergoing laparoscopic cholecystectomy.

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