Open AccessA comparative study of midazolam alone or in combination with dexmedetomidine or clonidine for awake fiberoptic intubation
Author(s) -
Noor Bano,
Pooja Singh,
Dheer Singh,
T Prabhakar
Publication year - 2019
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/aer.aer_64_19
Subject(s) - dexmedetomidine , anesthesia , sedation , midazolam , medicine , clonidine , intubation , sedative , hemodynamics , heart rate , mean arterial pressure , tracheal intubation , blood pressure
Awake fiberoptic intubation (AFOI) is the gold standard technique for managing patients with anticipated difficult airway. Conscious sedation is desirable, not only to make the procedure more tolerable and comfortable for the patient but also to ensure optimal intubating conditions. Ideal sedation regime for AFOI should provide comfort, cooperation, hemodynamic stability, and amnesia along with maintenance of spontaneous respiration. Several sedative agents have been assessed over the past two decades for this purpose but α2 agonists appear to be the favorable choice owing to its sedative, analgesic, amnestic, and sympatholytic properties along with good hemodynamic profile.