
Brain-relaxing effect of different diuretic regimens in supratentorial tumor surgery: A comparative study guided by optic nerve sheath diameter
Author(s) -
Mohamed Adel Aboelela,
Alrefaey Kandeel Alrefaey
Publication year - 2020
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/aer.aer_15_21
Subject(s) - medicine , furosemide , mannitol , anesthesia , intracranial pressure , diuretic , diuresis , urology , blood pressure , renal function , chemistry , organic chemistry
Hyperosmolar therapy is a well-established method to approach brain relaxation during craniotomy. Mannitol is used with a wide range of dosing regimens, combination with loop diuretics exerts a synergistic effect resulting in both reduction of the dose and its complications. Ultrasound measurement of optic nerve sheath diameter (ONSD) gives reliable information about intracranial pressure (ICP) and avoids overdosing and complications of osmotherapy.