Effect of combination of ketamine and propofol (ketofol) on cerebral oxygenation in neurosurgical patients: A randomized double-blinded controlled trial | Zendy

Ankur Luthra | Zendy; VishwanathaS Bhaire | Zendy; Nidhi Panda | Zendy; Rajeev Chauhan | Zendy; Deepak Rajappa | Zendy; Hemant Bhagat | Zendy

Open Access

Effect of combination of ketamine and propofol (ketofol) on cerebral oxygenation in neurosurgical patients: A randomized double-blinded controlled trial

Author(s) -

Ankur Luthra,

VishwanathaS Bhaire,

Nidhi Panda,

Rajeev Chauhan,

Deepak Rajappa,

Hemant Bhagat

Publication year - 2019

Publication title -

anesthesia essays and researches

Language(s) - English

Resource type - Journals

ISSN - 0259-1162

DOI - 10.4103/aer.aer_119_19

Subject(s) - propofol , medicine , anesthesia , fentanyl , ketamine

The effects of ketofol (a combination of ketamine and propofol) on systemic hemodynamics and requirement of opioids/Propofol have already been studied and published. However, there is paucity in the literature on the effects of ketofol on cerebral oxygenation. This study aims to compare the effects of ketofol (ketamine + propofol [1:5]) with propofol on cerebral oxygenation using jugular venous oxygen saturation (SjVO2), in patients undergoing surgical clipping of intracranial aneurysms.

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