Open AccessEffect of combination of ketamine and propofol (ketofol) on cerebral oxygenation in neurosurgical patients: A randomized double-blinded controlled trial
Author(s) -
Vishwanatha S Bhaire,
Nidhi Panda,
Ankur Luthra,
Rajeev Chauhan,
Deepak Rajappa,
Hemant Bhagat
Publication year - 2019
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/aer.aer_119_19
Subject(s) - propofol , medicine , anesthesia , fentanyl , ketamine
The effects of ketofol (a combination of ketamine and propofol) on systemic hemodynamics and requirement of opioids/Propofol have already been studied and published. However, there is paucity in the literature on the effects of ketofol on cerebral oxygenation. This study aims to compare the effects of ketofol (ketamine + propofol [1:5]) with propofol on cerebral oxygenation using jugular venous oxygen saturation (SjVO2), in patients undergoing surgical clipping of intracranial aneurysms.