Open AccessComparison of oral clonidine and gabapentin premedication for attenuation of pressor response to laryngoscopy and endotracheal intubation
Author(s) -
Vaishali Sharma,
Kamal Fotedar,
Ravi Kumar Goel
Publication year - 2020
Publication title -
al-banǧ. maqālāt wa abḥāṯ fī al-taẖdīr wa-al-in’āš
Language(s) - English
Resource type - Journals
ISSN - 0259-1162
DOI - 10.4103/aer.aer_114_20
Subject(s) - clonidine , anesthesia , medicine , premedication , laryngoscopy , gabapentin , intubation , placebo , hemodynamics , blood pressure , alternative medicine , pathology
During the administration of general anesthesia, direct laryngoscopy and endotracheal intubation cause an increase in heart rate, arterial pressure, and dysrhythmias in upto 90% of patients. These changes can be particularly hazardous for patients with cerebral or coronary diseases. Both clonidine and gabapentin have been used for anesthetic effects, but a better drug for controlling hemodynamic parameters is being investigated.