Open AccessHypokalemic paralysis as an initial presentation of Sjogren syndrome
Author(s) -
Durga Shankar Meena,
Deepak Kumar,
Gopal Krishana Bohra,
Sunil Kumar Bhambu
Publication year - 2020
Publication title -
annals of african medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.433
H-Index - 26
ISSN - 1596-3519
DOI - 10.4103/aam.aam_34_19
Subject(s) - medicine , hypokalemia , distal renal tubular acidosis , renal tubular acidosis , hypokalemic periodic paralysis , interstitial nephritis , periodic paralysis , paralysis , presentation (obstetrics) , sicca syndrome , gastroenterology , facial paralysis , dermatology , disease , pathology , surgery , acidosis , kidney
Sjogren syndrome (SS) is a systemic autoimmune disorder with predominant exocrine gland involvement leading to sicca symptoms. Among extraglandular manifestations, renal disease is the most common. Tubular interstitial nephritis and renal tubular acidosis (RTA) are the common presentations. Mild hypokalemia associated with distal RTA is common in SS, however, severe hypokalemia causing paralysis is unusual. We report the case of a 26-year-old female who presented with hypokalemic paralysis. On evaluation, distal RTA was diagnosed. Further evaluation showed positive SS-a/SS-b antibodies in high titer, which confirms the diagnosis of primary SS. Our report illustrates that SS is a rare but important cause of hypokalemic paralysis.