Open AccessEvaluation of neutrophil gelatinase-associated lipocalin and cystatin C as early markers of diabetic nephropathy
Author(s) -
Zeba Siddiqi,
Ritu Karoli,
Anupama Kaul,
Jalees Fatima,
Shishir Varshney,
Mohd Sameer Beg
Publication year - 2017
Publication title -
annals of african medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.433
H-Index - 26
ISSN - 1596-3519
DOI - 10.4103/aam.aam_12_17
Subject(s) - medicine , microalbuminuria , lipocalin , diabetic nephropathy , diabetes mellitus , nephropathy , albuminuria , cystatin c , gastroenterology , urinary system , dyslipidemia , kidney disease , urology , endocrinology , creatinine
Diabetes mellitus (DM) is a major cause of concern because of its increasing prevalence rate and related microvascular as well as macrovascular complications, including kidney disease. Microalbuminuria has been accepted as the earliest marker for diabetic nephropathy; however, a large proportion of renal impairment occurs in nonalbuminuric state. We planned to investigate the serum and urinary levels of the tubular damage markers (neutrophil gelatinase-associated lipocalin [NGAL] and cystatin C [Cys C]) in patients of type 2 diabetes to detect early kidney injury.