Open AccessA rare case of triple negative synchronous bilateral invasive ductal carcinoma of breast
Author(s) -
Abhishek Purkayastha,
Neelam Sharma,
Nishant Lohia
Publication year - 2016
Publication title -
archives of medicine and health sciences
Language(s) - English
Resource type - Journals
eISSN - 2321-6085
pISSN - 2321-4848
DOI - 10.4103/2321-4848.183345
Subject(s) - medicine , modified radical mastectomy , histopathology , progesterone receptor , radiology , ductal carcinoma , mastectomy , estrogen receptor , invasive ductal carcinoma , mammography , triple negative breast cancer , immunohistochemistry , metastasis , breast cancer , pathology , cancer
The occurrence of bilateral breast carcinoma is extremely rare with an incidence of 2-5% of all breast malignancies. We hereby report an unusual and interesting case of triple negative synchronous invasive ductal carcinoma (IDC) of bilateral breasts detected simultaneously in view of its rarity and therapeutic challenge it presented. A 55-year-old postmenopausal female presented with a history of lump bilateral breasts of 4 months duration. Fine needle aspiration cytology of both breast lumps showed IDC. Mammography showed Breast Imaging Reporting and Data System V both breasts. Metastatic workup was negative. She underwent bilateral modified radical mastectomy. Postoperative histopathology revealed IDC Grade III with estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2-neu negative on immunohistochemistry. She received adjuvant chemotherapy followed by locoregional radiotherapy to the right breast in view of nodal positivity. Presently on regular follow-up without any evidence of local recurrence or distant metastasis