Open AccessTeratoid Wilms tumour with chemotherapy resistance
Author(s) -
Renuka Gahine,
Shruti Srivastava,
Rabia Siddiqui,
Vikas Bombeshwar
Publication year - 2015
Publication title -
archives of medicine and health sciences
Language(s) - English
Resource type - Journals
eISSN - 2321-6085
pISSN - 2321-4848
DOI - 10.4103/2321-4848.171942
Subject(s) - medicine , nephrectomy , wilms' tumor , chemotherapy , wilms tumour , renal vein , neoplasm , radiation therapy , inferior vena cava , pathology , kidney , surgery , radiology
We present a case of Teratoid Wilms tumour (a rare histologic variant) in a 4 year old male who presented with an abdominal lump. Wilms Tumour with paracaval lymphadenopathy and tumour thrombi in right renal vein and inferior vena cava was made radiologically. FNAC report was suggestive of Wilms tumour and patient was subjected to 6 cycles of chemotherapy with not much reduction in size. Post nephrectomy histological diagnosis of Teratoid Wilms tumour was established. Resistance to chemotherapy and radiotherapy is thought to be due to presence of well differentiated histologic appearance. Teratoid Wilms tumour is usually not an aggressive neoplasm and prognosis is comparatively neoplasm and prognosis is comparatively good if the tumour is excised completely thus surgery being the best treatment