Open AccessUsefulness of Danaparoid sodium in patients with Heparin-induced thrombocytopenia after cardiac surgery
Author(s) -
Farzaneh Foroughinia,
Bahram Fariborz Farsad,
Kheirollah Gholami,
Somayeh Hajiahmadi
Publication year - 2015
Publication title -
journal of research in pharmacy practice
Language(s) - English
Resource type - Journals
eISSN - 2319-9644
pISSN - 2279-042X
DOI - 10.4103/2279-042x.155754
Subject(s) - medicine , heparin induced thrombocytopenia , complication , heparin , lepirudin , surgery , cardiac surgery , anticoagulant , low molecular weight heparin , bolus (digestion) , anesthesia , discovery and development of direct thrombin inhibitors , platelet , thrombin
Thrombocytopenia is a common problem in cardiovascular surgery patients. However, heparin-induced thrombocytopenia (HIT) is a rare but life-threatening complication of prophylaxis or treatment with heparin. Prompt management of HIT with an alternative anticoagulant is necessary due to the extreme risk of thrombotic complications. Therefore, we evaluated the effects of danaparoid in the treatment of HIT in patients with cardiac surgery who are at moderate to high risk of HIT.