Open AccessPlatelet-rich plasma application in chondrogenesis
Author(s) -
Azadeh Kabiri,
Ebrahim Esfandiari,
Abolghasem Esmaeili,
Batool Hashemibeni,
Abbas Pourazar,
Mohammad Mardani
Publication year - 2014
Publication title -
advanced biomedical research
Language(s) - English
Resource type - Journals
ISSN - 2277-9175
DOI - 10.4103/2277-9175.135156
Subject(s) - chondrogenesis , platelet rich plasma , growth factor , vascular endothelial growth factor , platelet derived growth factor , platelet derived growth factor receptor , medicine , basic fibroblast growth factor , fibroblast growth factor , transforming growth factor , platelet , cancer research , immunology , vegf receptors , endocrinology , mesenchymal stem cell , pathology , receptor
Platelet-rich plasma (PRP), an autologous derivative of whole blood, has been recently used in surgical treatment. PRP contains growth factors including transforming growth factor-β (TGF-β), insulin-like growth factor (IGF), platelet-derived growth factor (PDGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF) and also bioactive proteins that influence the healing of tendon, ligament, muscle, and bone. This article describes the current clinical applications of PRP in chondrogenesis. This study reviews and evaluates the studies that have been published in the field of chondrogenesis. All aspects of using PRP in chondrogenesis are reviewed