Open AccessA new dawn in modern perio-diagnostics: Saliva and gingival crevicular fluid
Author(s) -
Harpreet Singh Grover,
Rohit Saini,
Pearl Bhardwaj,
Amit Bhardwaj
Publication year - 2014
Publication title -
journal of dental and allied sciences
Language(s) - English
Resource type - Journals
eISSN - 2277-6672
pISSN - 2277-4696
DOI - 10.4103/2277-4696.159091
Subject(s) - saliva , exudate , periodontal disease , disease , biological fluids , medicine , dentistry , differential diagnosis , transudate , pathology , chemistry , pleural fluid , chromatography , pleural effusion
Periodontal disease is a chronic microbial infection. There is a need for the evolvement of contemporary diagnostic tests to improve the clinical management. Molecular arrays for the detection of biomarkers on the different stages of the disease help in understanding various mediators of the disease process. This evolutionary process has promoted the discovery of new biomarkers. A periodontal diagnostic tool provides pertinent information for differential diagnosis and localization of disease. Human saliva is an easily accessible biochemical fluid, which is similar to blood in various biological aspects. Gingival crevicular fluid is an inflammatory exudate that represents serum components overlaid with products from local physiologic phenomena, and has diagnostic value