Open AccessNeonatal cholestasis due to primary sclerosing cholangitis
Author(s) -
Naman S. Shetty,
Ira Shah
Publication year - 2016
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/2249-4863.201154
Subject(s) - medicine , primary sclerosing cholangitis , cholestasis , gastroenterology , neonatal cholestasis , bile duct , jaundice , liver biopsy , obstructive jaundice , fibrosis , biopsy , disease , biliary atresia , liver transplantation , transplantation
Neonatal cholestasis is rarely caused due to primary sclerosing cholangitis, which is an inflammatory disease of the bile ducts, which results in obstructive fibrosis of the ducts. A 7-month-old male child presented with jaundice along with high-colored urine and clay-colored stools since birth. Liver biopsy showed mild bile duct proliferation with cholangioles showing bile and thrombi suggestive of primary sclerosing cholangitis.