Open AccessKyrle′s disease in a patient of diabetes mellitus and chronic renal failure on dialysis
Author(s) -
Pragya A Nair,
Nidhi B Jivani,
Nilofar G Diwan
Publication year - 2015
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/2249-4863.154678
Subject(s) - medicine , chronic renal failure , diabetes mellitus , dermis , cryotherapy , dermatology , epidermis (zoology) , dialysis , disease , pathology , surgery , endocrinology , anatomy
Kyrle's disease (KD) is an acquired perforating dermatosis associated with an underlying disorder such as diabetes mellitus or chronic renal failure. It presents as multiple discrete, eruptive papules with a central crust or plug, often on the lower extremities. A keratotic plug is seen histologically in an atrophic epidermis and may penetrate the papillary dermis with transepidermal elimination of keratotic debris without collagen or elastic fibers. Various therapies have been reported that include cryotherapy, laser therapy, narrow-band ultraviolet B and use of topical or systemic retinoids. Hereby a case of 64-year-old male, a known case of diabetes mellitus, hypertension and chronic renal failure who developed KD is presented.