Open AccessDrug-induced hepatitis and the risk factors for liver injury in pulmonary tuberculosis patients
Author(s) -
Gajanan S Gaude,
Alisha Chaudhury,
Jyothi Hattiholi
Publication year - 2015
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/2249-4863.154661
Subject(s) - medicine , tuberculosis , hypoalbuminemia , rifampicin , hepatitis , risk factor , liver disease , population , cohort study , surgery , pathology , environmental health
Short-course chemotherapy containing rifampicin and isoniazid in combination has proved to be highly effective in the treatment of tuberculosis, but one of its adverse effects is hepatotoxicity. Various risk factors have been found to be associated with drug-induced liver injury (DILI) in general population. The study aimed to determine the prevalence of drug-induced hepatitis and the risk factors associated with the DILI among the patients of pulmonary tuberculosis in Indian patients.