Open AccessEosinophilia induced by clozapine: A report of two cases and review of the literature
Author(s) -
Jitender Aneja,
Nidhi Sharma,
Shalvi Mahajan,
Subho Chakrabarti,
Sandeep Grover
Publication year - 2015
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/2249-4863.152269
Subject(s) - eosinophilia , medicine , clozapine , leukocytosis , schizophrenia (object oriented programming) , antipsychotic , adverse effect , psychosis , dermatology , pediatrics , psychiatry
Clozapine, an atypical antipsychotic, has been used in the treatment of schizophrenia and other psychotic disorders. Although it has good therapeutic effect but many a time it use is overridden by the associated adverse effects which range from minor to severe life-threatening events. There has been extensive literature for severe side effects like leukocytosis but limited data are available for transient eosinophilia. Here, we present two cases of benign transient eosinophilia and discuss the importance of recognizing eosinophilia while using clozapine.