Open AccessUnusual neonatal presentation of type I leukocyte adhesion deficiency
Author(s) -
Bonny Jasani,
Ruchi Nanavati,
Nandkishor S Kabra
Publication year - 2014
Publication title -
journal of clinical neonatology/journal of clinical neonatology
Language(s) - English
Resource type - Journals
eISSN - 1658-6093
pISSN - 2249-4847
DOI - 10.4103/2249-4847.134703
Subject(s) - medicine , leukocyte adhesion deficiency , leukemoid reaction , presentation (obstetrics) , pediatrics , immunodeficiency , adhesion , immunology , surgery , immune system , cd18 , chemistry , organic chemistry , integrin alpha m
Leukocyte adhesion deficiency type I is an extremely serious and rare form of congenital immunodeficiency with recurrent episodes of infection since neonatal period. It is usually diagnosed in childhood, but if diagnosed early in neonatal period then definitive treatment can be instituted early with promising results. High index of suspicion is necessary to diagnose this condition in neonates. Neonate may present with serious bacterial infections with a leukemoid reaction.