Open AccessHost-bacterial interplay in periodontal disease
Author(s) -
Rudrakshi Chickanna,
Munivenkatappa Lakshmaiah Venkatesh Prabhuji,
Munaga Shanmukha Venkata Nagarjuna
Publication year - 2015
Publication title -
journal of international clinical dental research organization
Language(s) - English
Resource type - Journals
eISSN - 2231-5357
pISSN - 2231-0754
DOI - 10.4103/2231-0754.153495
Subject(s) - periodontal disease , host (biology) , disease , host factors , medicine , biology , dentistry , immunology , pathology , genetics , virus
A literature search was performed using MEDLINE (PubMed) and other electronic basis from 1991 to 2014. Search included books and journals based on the systematic and critical reviews, in vitro and in vivo clinical studies on molecular basis of host microbial interactions. Clearly, an understanding of the host susceptibility factor in addition to microbial factors by elucidating the molecular basis offers opportunity for therapeutic manipulation of advancing periodontal destruction. One of the hallmarks of pathogenesis is the ability of pathogenic organisms to invade surrounding tissues and to evade the host defence. This paper focuses the general overview of molecular mechanisms involved in the microbiota and host response to bacterial inimical behavior in periodontics