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Maxillofacial reconstruction on a young child with huge aggressively growing lesion is a tough situation owing to several limiting factors. Besides the other factors, impact of the growing lesion on the psychology of the child also needs to be considered. This manuscript reports a case of an 18-month-old boy with juvenile cemento-ossifying fibroma in whom removal of a large portion of the jaws was required. The regeneration of the jaw bones with the help of protein signal guided reconstruction using bone morphogenetic protein-2 is described. Long-term follow-up of the patient with dental implants placed on the neo-osteogenic bone is reported.

Protein-signaled guided total jaw regeneration in infantile total mandibular resection