Open AccessPreparation and evaluation of a novel oral delivery system for low molecular weight heparin
Author(s) -
Nallaguntla Lavanya,
Y. Indira Muzib,
Jithan Aukunuru,
Umamahesh Balekari
Publication year - 2016
Publication title -
international journal of pharmaceutical investigation
Language(s) - English
Resource type - Journals
eISSN - 2230-973X
pISSN - 2230-9713
DOI - 10.4103/2230-973x.187351
Subject(s) - liposome , permeation , differential scanning calorimetry , fourier transform infrared spectroscopy , bioavailability , materials science , chromatography , chemistry , nuclear chemistry , chemical engineering , pharmacology , nanotechnology , biochemistry , membrane , medicine , physics , engineering , thermodynamics
The objective of the present work was to prepare and evaluate a novel oral formulation for systemic delivery of low molecular weight heparin (LMWH). The formulation consisted of Eudragit S 100-coated positively charged liposomes encapsulating LMWH and a penetration enhancer.