Open AccessCentral precocious puberty due to hypothalamic hamartoma in a six-month-old infant girl
Author(s) -
Narendra Kotwal,
Uday Yanamandra,
Anil Me,
Velu Nair
Publication year - 2012
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.98027
Subject(s) - girl , medicine , hypothalamic hamartoma , central precocious puberty , precocious puberty , menarche , pediatrics , incidence (geometry) , hamartoma , endocrinology , hormone , psychology , developmental psychology , physics , optics , pathology
Precocious puberty defined as an onset of puberty below eight years in girls and nine years in boys, has an incidence of approximately 1 / 5,000 - 1 / 10,000 subjects with a female / male ratio of 20: 1. It is etiologically classified broadly as central and peripheral. We present to you a case of isosexual (central), precocious puberty in a 16-month-old girl, who was symptomatic since the age of six months, and was later, diagnosed to have hypothalamic hamartoma. It is one of the earliest case records ever in the medical literature of menarche, at an extremely early age (six-month-old child) secondary to a central cause.