Open AccessAcromegaly associated with a symptomatic Rathke′s cyst
Author(s) -
Vishal Gupta,
Ashley Grossman,
Aneesa Kapadia,
Kiran Thorat
Publication year - 2011
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.81950
Subject(s) - acromegaly , medicine , pituitary adenoma , cyst , magnetic resonance imaging , neurosurgery , somatotropic cell , craniopharyngioma , growth hormone , transsphenoidal surgery , pituitary neoplasm , radiology , adenoma , pathology , pituitary gland , hormone
Our aim is to describe a case of acromegaly that was associated with symptomatic Rathke's cyst. We describe a young male student without any significant family history who presented with clinical and biochemical features consistent with growth hormone excess, which was confirmed with dynamic testing. He also described a persistent headache predating symptoms of growth hormone excess by 4 years. Magnetic resonance imaging (MRI) of the pituitary showed a large sellar mass which was thought to be a somatotroph adenoma. Trans-sphenoidal surgery was performed; however, a colloid lesion was identified by the neurosurgeon that proved to be a Rathke's cyst. The association of acromegaly with Rathke's cyst is very rare, with less than 10 cases found to be reported on review of literature. This is the first report from India.