Open AccessProlonged adrenal insufficiency after unilateral adrenalectomy for Cushing′s Syndrome
Author(s) -
Bindu Kulshreshtha,
Aashima Arora,
Aditya Aggarwal,
Minakshi Bhardwaj
Publication year - 2015
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.152794
Subject(s) - medicine , adrenalectomy , adrenal insufficiency , cushing syndrome , bilateral adrenalectomy , surgery
The contralateral healthy adrenal in patients undergoing unilateral adrenalectomy for Cushing's is known to be suppressed temporarily and forms the basis of peri and postoperative steroids. We present four cases of Cushing's who had prolonged adrenal insufficiency with continued requirement for steroids for periods ranging 1-4 years after unilateral adrenalectomy for Cushing's. We further review literature regarding the recovery of the hypothalamo pituitary adrenal axis postsurgery in patients with Cushing's syndrome.