Open AccessEndocrine and metabolic disease: Confocal microscopy as a diagnostic aid
Author(s) -
Jaikrit Bhutani,
Raja Chandra Chakinala,
Sukriti Bhutani,
Shruti Sachdeva
Publication year - 2015
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.146877
Subject(s) - medicine , disease , diabetic neuropathy , diabetes mellitus , intensive care medicine , biomarker , pathological , pathology , endocrine system , confocal microscopy , bioinformatics , endocrinology , biochemistry , chemistry , hormone , microbiology and biotechnology , biology
Diabetes is a systemic disease associated with many complications. These can be prevented and managed effectively if detected promptly. Confocal microscopy (CFM) is a diagnostic tool which has the potential to help in early detection of disease and timely management. CFM has the potential to serve as an excellent noninvasive modality for in vivo imaging and morphological analysis, which can aid us in assessing and monitoring various infectious and pathological diseases at the cellular level. Besides ophthalmological indications, CFM has shown good sensitivity and specificity for identifying those at risk of neuropathy and foot ulceration, monitoring evolution and therapeutic response in a wide range of neuropathies apart from diabetic neuropathy. Through this communication, we aim to sensitize the endocrinologists towards cerebral cavernous malformation as a biomarker to evaluate potential outcomes and therapies in human diabetic neuropathy.