Open AccessMilk alkali syndrome induced by calcitriol and calcium bicarbonate in a patient with hypoparathyroidism
Author(s) -
Eda Altun,
Bülent Kaya,
Saime Paydaş,
Mustafa Balal
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.119568
Subject(s) - medicine , metabolic alkalosis , hypoparathyroidism , calcitriol , ingestion , calcium , gastroenterology , bartter syndrome , sodium bicarbonate , endocrinology , alkalosis , hypokalemia , acidosis , chemistry
The milk-alkali syndrome (MAS) was a common cause of hypercalcemia, metabolic alkalosis, and renal failure in the early 20(th) century. This syndrome was first recognized secondary to treatment of peptic ulcer disease with milk and absorbable alkali. Its incidence fell after the introduction of H2-blocker and proton pump inhibitor. Persistent ingestion of calcium carbonate and vitamin D caused MAS. We report a patient presenting with a triad of hypercalcemia, metabolic alkalosis and renal failure secondary to treatment of idiopathic hypoparathyroidism.