Open AccessEndocrine management of male subfertility
Author(s) -
Belinda George,
Ganapathi Bantwal
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.119500
Subject(s) - endocrine system , infertility , medicine , aromatase , male infertility , gynecology , gonadotropin , spermatogenesis , bioinformatics , endocrinology , hormone , pregnancy , biology , cancer , breast cancer , genetics
Infertility in a couple is defined as failure to conceive after 12 months of regular unprotected intercourses. Male infertility due to impaired spermatogenesis may result from hypothalamic, pituitary or testicular disorders. Medical management of infertility associated with gonadotropin deficiencies have high success rate, but for primary testicular failure assisted reproduction techniques (ART) with adjunctive endocrine manipulation remains the best therapeutic option. This article discusses various therapeutic options and regimes using gonadotropins, anti-estrgens, aromatase inhibitors in management of male subfertiltiy.