Open AccessGlucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment
Author(s) -
Anu Gupta,
Yashdeep Gupta
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.117215
Subject(s) - myopathy , glucocorticoid , medicine , pathophysiology , muscle weakness , atrophy , weakness , proximal muscle weakness , endocrinology , anatomy , muscle biopsy , biopsy
Glucocorticoid-induced myopathy is the most common type of drug-induced myopathy. Nearly 60% of patients with Cushing's syndrome have muscle weakness. Glucocorticoid-induced muscle atrophy affects mainly fast-twitch glycolytic muscle fibers (type IIb fibers). This brief review will discuss the pathophysiology behind glucocorticoid-induced myopathy, along with diagnostic features and treatment.