Open AccessRenal phosphate handling: Physiology
Author(s) -
Narayan Prasad,
Dharmendra Bhadauria
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.113752
Subject(s) - parathyroid hormone , phosphate , phosphorus , endocrinology , medicine , vitamin d and neurology , klotho , kidney , hormone , biology , biochemistry , chemistry , calcium , organic chemistry
Phosphorus is a common anion. It plays an important role in energy generation. Renal phosphate handling is regulated by three organs parathyroid, kidney and bone through feedback loops. These counter regulatory loops also regulate intestinal absorption and thus maintain serum phosphorus concentration in physiologic range. The parathyroid hormone, vitamin D, Fibrogenic growth factor 23 (FGF23) and klotho coreceptor are the key regulators of phosphorus balance in body.