Open AccessPropylthiouracil induced leukocytoclastic vasculitis: A rare manifestation
Author(s) -
Semra Aytürk,
Mustafa Demır,
Selçuk Yaylacı,
Ali Tamer
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.109665
Subject(s) - medicine , propylthiouracil , leukocytoclastic vasculitis , graves' disease , vasculitis , dermatology , antibody , methimazole , disease , immunology , pathology , thyroid
Propylthiouracil (PTU) is a common drug used in patients with hyperthyroidism. It may cause perinuclearantineutrophil cytoplasmic antibodies (p-ANCA) in few patients with Graves' disease. This antibody has been associated with different forms of vasculitis. We report a patient who presented with cutaneous manifestations of leukocytoclasticvasculitis with simultaneous development of p-ANCAs during PTU therapy for Graves' disease.